{{Rsnum
|rsid=12899449
|Chromosome=15
|position=38703290
|Orientation=plus
|GMAF=0.1731
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 67.0 | 29.4 | 3.7
| HCB | 94.9 | 5.1 | 0.0
| JPT | 90.3 | 9.7 | 0.0
| YRI | 70.7 | 25.9 | 3.4
| ASW | 64.9 | 33.3 | 1.8
| CHB | 94.9 | 5.1 | 0.0
| CHD | 95.4 | 3.7 | 0.9
| GIH | 70.0 | 30.0 | 0.0
| LWK | 70.0 | 29.1 | 0.9
| MEX | 66.7 | 28.1 | 5.3
| MKK | 54.4 | 39.6 | 6.0
| TSI | 49.0 | 48.0 | 2.9
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs12899449
|PubMedID=18711365
|Condition=Bipolar disorder
|Gene=C15orf53, RASGRP1
|Risk Allele=
|pValue=4.00E-007
|OR=1.2
|95CI=
|OA=1
}}

{{PharmGKB
|RSID=rs12899449
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18711365; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder (Initial Sample Size: 1,098 cases, 1,267 controls; Replication Sample Size: 4,387 cases, 6,209 controls). This variant is associated with Bipolar disorder.
|Drugs=
|Drug Classes=
|Diseases=Bipolar Disorder
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356411
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12899449
|overall_frequency_n=23
|overall_frequency_d=128
|overall_frequency=0.179688
|n_genomes=18
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}