{{Rsnum
|rsid=12911738
|Gene=CASC5
|Chromosome=15
|position=40611486
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=G
|GMAF=0.2994
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CASC5
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 20.0 | 80.0
| HCB | 52.3 | 42.4 | 5.3
| JPT | 46.8 | 45.0 | 8.1
| YRI | 0.0 | 16.4 | 83.6
| ASW | 0.0 | 0.0 | 0.0
| CHB | 52.3 | 42.4 | 5.3
| CHD | 46.7 | 41.1 | 12.1
| GIH | 11.3 | 49.5 | 39.2
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 1.3 | 30.9 | 67.8
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=12911738
|allele=G
|frequency=0.892
|uid=1103645593426
|type=homozygous_SNP
|hugo=CASC5
|ensembl gene=ENSG00000137812
|ensembl transcript=ENST00000346991
|sift=
|disease=A chromosomal aberration involving CASC5 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX. May give rise to a MLL-CASC5 fusion protein.
}}

{{GET Evidence
|gene=CASC5
|aa_change=Thr87Ala
|aa_change_short=T87A
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12911738
|overall_frequency_n=4085
|overall_frequency_d=4734
|overall_frequency=0.862907
|n_genomes=36
|n_genomes_annotated=0
|n_haplomes=60
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}