{{Rsnum
|rsid=12914385
|Gene=CHRNA3
|Chromosome=15
|position=78606381
|Orientation=plus
|GMAF=0.3127
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CHRNA3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 32.7 | 49.6 | 17.7
| HCB | 52.9 | 44.1 | 2.9
| JPT | 46.4 | 44.6 | 8.9
| YRI | 65.1 | 32.9 | 2.1
| ASW | 59.6 | 35.1 | 5.3
| CHB | 52.9 | 44.1 | 2.9
| CHD | 46.8 | 47.7 | 5.5
| GIH | 62.0 | 32.0 | 6.0
| LWK | 57.4 | 40.7 | 1.9
| MEX | 55.2 | 39.7 | 5.2
| MKK | 60.6 | 34.8 | 4.5
| TSI | 31.7 | 45.5 | 22.8
| HapMapRevision=28
}}{{PMID Auto
|PMID=19654303
|Title=Deciphering the Impact of Common Genetic Variation on Lung Cancer Risk: A Genome-Wide Association Study
|OA=1
}}

{{omim
|id=612052
|rsnum=12914385
}}

{{PMID Auto GWAS
|PMID=21946350
|Trait=None
|Title=Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|RiskAllele=T
|Pval=5E-7
|OR=0.0250
|ORtxt=[0.015-0.035] unit decrease
|OA=1
}}

{{PMID Auto
|PMID=18759969
|Title=In search of causal variants: refining disease association signals using cross-population contrasts.
|OA=1
}}

{{PMID Auto
|PMID=19247474
|Title=Genome-wide and candidate gene association study of cigarette smoking behaviors.
|OA=1
}}

{{PMID Auto
|PMID=19836008
|Title=A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
|OA=1
}}

{{PMID Auto
|PMID=19955392
|Title=Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.
}}

{{PMID Auto
|PMID=20808433
|Title=Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.
|OA=1
}}

{{PMID Auto
|PMID=21436384
|Title=Genetic variability of smoking persistence in African Americans.
|OA=1
}}

{{PMID Auto
|PMID=22430809
|Title=Association between a Genome-Wide Association Study-Identified Locus and the Risk of Lung Cancer in Japanese Population.
}}

{{PMID Auto GWAS
  |PMID=23022100
  |Trait=Serum albumin level
  |Title=Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
  |RiskAllele=C
  |Pval=6E-7
  |OR=.01
  |ORtxt=[0.0048-0.0106] unit increase
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}