{{Rsnum
|rsid=12951053
|Gene=TP53
|Chromosome=17
|position=7674089
|Orientation=plus
|GMAF=0.1635
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TP53
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 82.3 | 15.9 | 1.8
| HCB | 42.3 | 46.7 | 10.9
| JPT | 57.5 | 32.7 | 9.7
| YRI | 81.0 | 17.7 | 1.4
| ASW | 68.4 | 24.6 | 7.0
| CHB | 42.3 | 46.7 | 10.9
| CHD | 45.0 | 43.1 | 11.9
| GIH | 74.3 | 22.8 | 3.0
| LWK | 67.3 | 30.0 | 2.7
| MEX | 69.0 | 29.3 | 1.7
| MKK | 80.8 | 18.6 | 0.6
| TSI | 81.4 | 18.6 | 0.0
| HapMapRevision=28
}}

{{PMID|17683073}} [[rs17887200]] and [[rs12951053]] associated with ER negative [[breast cancer]] tumors (1.48 (1.11-1.93) p-trend = 0.01 and 1.29 (1.06-1.58) p-trend = 0.009, respectively)

A study population including a total of 5,206 invasive [[ovarian cancer]] cases (2,829 of which were serous) and 8,790 controls found an association between [[rs12951053]] and serous invasive cancer (median per allele odds ratio 1.19, CI: 1.01-1.38).{{PMID|19276375|OA=1
}}

{{ neighbor
| rsid = 28934576
| distance = 287
}}
{{ neighbor
| rsid = 28934577
| distance = 104
}}

{{PMID Auto
|PMID=19423538
|Title=Common Genetic Variation in TP53 and Risk of Human Papillomavirus Persistence and Progression to CIN3/Cancer Revisited
|OA=1
}}

{{PMID Auto
|PMID=20386703
|Title=Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer
|OA=1
}}

{{PMID Auto
|PMID=22291954
|Title=Association between Variations in Cell Cycle Genes and Idiopathic Pulmonary Fibrosis
|OA=1
}}

{{PMID Auto
|PMID=17301252
|Title=Common genetic variation in TP53 is associated with lung cancer risk and prognosis in African Americans and somatic mutations in lung tumors.
}}

{{PMID Auto
|PMID=17449902
|Title=Genetic variation in TP53 and risk of breast cancer in a population-based case control study.
}}

{{PMID Auto
|PMID=18640487
|Title=Association of donor inflammation- and apoptosis-related genotypes and delayed allograft function after kidney transplantation.
|OA=1
}}

{{PMID Auto
|PMID=18978339
|Title=Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.
|OA=1
}}

{{PMID Auto
|PMID=21536413
|Title=POMC and TP53 genetic variability and risk of basal cell carcinoma of skin: Interaction between host and genetic factors.
}}

{{PMID Auto
|PMID=23124483
|Title=Correlation of telomere length shortening with TP53 somatic mutations, polymorphisms and allelic loss in breast tumors and esophageal cancer.
}}

{{PMID Auto
|PMID=23435014
|Title=Differential mutation profiles and similar intronic TP53 polymorphisms in asbestos-related lung cancer and pleural mesothelioma.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}