{{Rsnum
|rsid=1295686
|Gene=IL13
|Chromosome=5
|position=132660151
|Orientation=plus
|GMAF=0.388
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IL13
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 3.5 | 36.3 | 60.2
| HCB | 11.7 | 44.5 | 43.8
| JPT | 8.8 | 42.5 | 48.7
| YRI | 55.1 | 36.7 | 8.2
| ASW | 31.6 | 54.4 | 14.0
| CHB | 11.7 | 44.5 | 43.8
| CHD | 11.0 | 37.6 | 51.4
| GIH | 6.9 | 31.7 | 61.4
| LWK | 56.4 | 33.6 | 10.0
| MEX | 20.7 | 55.2 | 24.1
| MKK | 25.6 | 50.0 | 24.4
| TSI | 6.9 | 27.5 | 65.7
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20860503
|Trait=None
|Title=A large-scale, consortium-based genomewide association study of asthma
|RiskAllele=T
|Pval=1E-7
|OR=1.15
|ORtxt=[1.09-1.20]
}}

{{PMID Auto
|PMID=21050946
|Title=Does genetic regulation of IgE begin in utero? Evidence from T(H)1/T(H)2 gene polymorphisms and cord blood total IgE
|OA=1
}}

{{PMID Auto
|PMID=22515947
|Title=Associations Between Pro- and Anti-Inflammatory Cytokine Genes and Breast Pain in Women Prior to Breast Cancer Surgery
|OA=1
}}

{{PMID Auto
|PMID=22075330
|Title=A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study
|OA=1
}}

{{PMID Auto
|PMID=15660293
|Title=No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=15726497
|Title=Gene-environment interaction effects on the development of immune responses in the 1st year of life.
|OA=1
}}

{{PMID Auto
|PMID=16449530
|Title=Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.
|OA=1
}}

{{PMID Auto
|PMID=17303794
|Title=Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.
|OA=1
}}

{{PMID Auto
|PMID=17346294
|Title=IL13 gene polymorphism association with cord serum immunoglobulin E.
|OA=1
}}

{{PMID Auto
|PMID=18056382
|Title=Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.
|OA=1
}}

{{PMID Auto
|PMID=18186920
|Title=IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study.
|OA=1
}}

{{PMID Auto
|PMID=18410415
|Title=Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood.
|OA=1
}}

{{PMID Auto
|PMID=18625055
|Title=Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis.
|OA=1
}}

{{PMID Auto
|PMID=18676870
|Title=Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.
|OA=1
}}

{{PMID Auto
|PMID=18687755
|Title=Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population.
|OA=1
}}

{{PMID Auto
|PMID=19131662
|Title=A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
|OA=1
}}

{{PMID Auto
|PMID=19263529
|Title=Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.
|OA=1
}}

{{PMID Auto
|PMID=19330901
|Title=Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.
|OA=1
}}

{{PMID Auto
|PMID=19356949
|Title=Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.
|OA=1
}}

{{PMID Auto
|PMID=19559392
|Title=A candidate gene association study of 77 polymorphisms in migraine.
|OA=1
}}

{{PMID Auto
|PMID=19956101
|Title=Overview of the Rapid Response data.
|OA=1
}}

{{PMID Auto
|PMID=19956102
|Title=Evidence for association of the TCF7 locus with type I diabetes.
|OA=1
}}

{{PMID Auto
|PMID=19956109
|Title=The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.
|OA=1
}}

{{PMID Auto
|PMID=20015396
|Title=Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.
|OA=1
}}

{{PMID Auto
|PMID=20403202
|Title=Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study.
|OA=1
}}

{{PMID Auto
|PMID=21111021
|Title=Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine.
}}

{{PMID Auto
|PMID=21320344
|Title=Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.
|OA=1
}}

{{PMID Auto GWAS
  |PMID=23042114
  |Trait=Atopic dermatitis
  |Title=Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
  |RiskAllele=T
  |Pval=2E-6
  |OR=1.22
  |ORtxt=[NR]
  }}

{{PMID Auto
|PMID=23841068
|Title=Interleukin-13 +1923C/T Polymorphism Is Associated with Asthma Risk: A Meta-Analysis
|OA=1
}}

{{PMID Auto GWAS
  |PMID=23886662
  |Trait=Atopic dermatitis
  |Title=A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
  |RiskAllele=A
  |Pval=2E-17
  |OR=1.38
  |ORtxt=[1.283-1.49]
  |OA=1
}}

{{PMID Auto
|PMID=23028483
|Title=Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.
|OA=1
}}

{{PMID Auto GWAS
  |PMID=24241537
  |Trait=Asthma (childhood, severe)
  |Title=A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
  |RiskAllele=T
  |Pval=2E-6
  |OR=1.31
  |ORtxt=[1.17-1.48]
  }}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}