{{Rsnum
|rsid=12982744
|Gene=DOT1L
|Chromosome=19
|position=2177194
|Orientation=plus
|GMAF=0.2585
|Gene_s=DOT1L
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 33.8 | 53.8 | 12.3
| HCB | 60.0 | 37.8 | 2.2
| JPT | 37.8 | 53.3 | 8.9
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 60.0 | 37.8 | 2.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=22566624
|Title=Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis
|OA=1
}}
{{PMID Auto GWAS
  |PMID=20881960
  |Trait=Height
  |Title=Hundreds of variants clustered in genomic loci and biological pathways affect human height.
  |RiskAllele=C
  |Pval=3E-16
  |OR=.03
  |ORtxt=[NR] unit decrease
  |OA=1
}}{{PMID Auto
|PMID=23505243
|Title=The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males.
|OA=1
}}
{{PMID Auto
|PMID=25005768
|Title=Association Between Single Nucleotide Polymorphisms of DOT1L Gene and Risk of Knee Osteoarthritis in a Chinese Han Population
}}