{{Rsnum
|rsid=13031859
|Gene=OTOF
|Chromosome=2
|position=26519093
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.281
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=OTOF
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 22.3 | 47.3 | 30.4
| HCB | 0.0 | 13.9 | 86.1
| JPT | 0.9 | 16.8 | 82.3
| YRI | 0.0 | 4.8 | 95.2
| ASW | 3.5 | 28.1 | 68.4
| CHB | 0.0 | 13.9 | 86.1
| CHD | 1.9 | 15.9 | 82.2
| GIH | 10.9 | 42.6 | 46.5
| LWK | 0.0 | 12.7 | 87.3
| MEX | 31.0 | 41.4 | 27.6
| MKK | 5.1 | 35.3 | 59.6
| TSI | 18.6 | 57.8 | 23.5
| HapMapRevision=28
}}

{{Venter SNP
|rsid=13031859
|allele=A
|frequency=0.458
|uid=1103658049716
|type=homozygous_SNP
|hugo=OTOF
|ensembl gene=ENSG00000115155
|ensembl transcript=ENST00000380509
|sift=TOLERATED
|disease=Defects in OTOF are the cause of nonsyndromic autosomal recessive deafness 9 (DFNB9) (MIM:601071).
}}

{{ClinVar
|rsid=13031859
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=26741961
|CHROM=2
|GMAF=0.2811
|dbSNPBuildID=121
|SSR=0
|SAO=1
|VP=0x050360000000150517100101
|GENEINFO=OTOF:9381
|GENE_NAME=OTOF
|GENE_ID=9381
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000002.11:g.26741961G>A
|CLNORIGIN=0
|CLNSIG=2
|Tags=PM;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD
|CAF=0.719; 0.281
|CLNACC=RCV000021048.1; RCV000041497.1
|CLNDBN=Deafness, autosomal recessive 9; AllHighlyPenetrant
|CLNDSDB=GeneReviews:GeneReviews:MedGen:OMIM:Orphanet; MedGen
|CLNDSDBID=NBK1251:NBK1434:C1832828:601071:90636; CN169374
|CLNSRC=GeneReviews
|CLNSRCID=NBK1251
|COMMON=1
|Disease=Deafness; AllHighlyPenetrant
}}

{{GET Evidence
|gene=OTOF
|aa_change=Arg82Cys
|aa_change_short=R82C
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs13031859
|overall_frequency_n=3928
|overall_frequency_d=10756
|overall_frequency=0.365192
|n_genomes=23
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.006
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=8
|autoscore=3
|n_web_uneval=2
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}