{{Rsnum
|rsid=13119723
|Gene=KIAA1109
|Chromosome=4
|position=122297158
|Orientation=plus
|GMAF=0.06841
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=KIAA1109
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 78.8 | 19.5 | 1.8
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 94.7 | 5.3 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 82.2 | 16.8 | 1.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 96.6 | 3.4 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 79.2 | 16.8 | 4.0
| HapMapRevision=28
}}Of SNPs outside the HLA region, this SNP and one other ([[rs6822844]]) in the region of the [[IL21]] gene showed the strongest association with [[celiac disease]] in a study of ~800 Caucasian patients and a meta-analysis of two further populations.{{PMID|17558408|OA=1
}}

{{PMID Auto
|PMID=19455118
|Title=Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease
}}
{{PMID Auto
|PMID=19201773
|Title=Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis
|OA=1
}}

{{omim
|desc=CELIAC DISEASE, SUSCEPTIBILITY TO, 6; CELIAC6
|id=611598
|rsnum=13119723
}}

{{omim
|desc=KIAA1109 GENE; KIAA1109
|id=611565
|rsnum=13119723
}}

{{PMID Auto
|PMID=20184734
|Title=The 4q27 locus and familial prostate cancer risk
|OA=1
}}

{{PMID Auto GWAS
|PMID=20453842
|Trait=Rheumatoid arthritis
|Title=Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lock
|RiskAllele=A
|Pval=7E-7
|OR=1.12
|ORtxt=[NR]
}}

{{PMID Auto
|PMID=22355377
|Title=Caucasian and asian specific rheumatoid arthritis risk Loci reveal limited replication and apparent allelic heterogeneity in north indians
|OA=1
}}

{{PMID Auto
|PMID=18311140
|Title=Newly identified genetic risk variants for celiac disease related to the immune response.
|OA=1
}}

{{PMID Auto
|PMID=18369459
|Title=A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
|OA=1
}}

{{PMID Auto
|PMID=18418394
|Title=Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families.
}}

{{PMID Auto
|PMID=19061490
|Title=FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease.
|OA=1
}}

{{PMID Auto
|PMID=19176549
|Title=Genome-wide association analysis by lasso penalized logistic regression.
|OA=1
}}

{{PMID Auto
|PMID=20553587
|Title=Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.
|OA=1
}}

{{PMID Auto
|PMID=21304239
|Title=Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}