{{Rsnum
|rsid=13157656
|Gene=C7
|Chromosome=5
|position=40964750
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=C
|GMAF=0.1809
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=C7
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 59.8 | 34.8 | 5.4
| HCB | 59.9 | 35.8 | 4.4
| JPT | 63.7 | 31.0 | 5.3
| YRI | 95.2 | 4.8 | 0.0
| ASW | 86.0 | 14.0 | 0.0
| CHB | 59.9 | 35.8 | 4.4
| CHD | 65.1 | 32.1 | 2.8
| GIH | 41.4 | 39.4 | 19.2
| LWK | 94.5 | 5.5 | 0.0
| MEX | 53.4 | 41.4 | 5.2
| MKK | 96.2 | 3.2 | 0.6
| TSI | 56.9 | 37.3 | 5.9
| HapMapRevision=28
}}{{Venter SNP
|rsid=13157656
|allele=C
|frequency=0.237
|uid=1103654083832
|type=heterozygous_SNP
|hugo=C7
|ensembl gene=ENSG00000112936
|ensembl transcript=ENST00000313164
|sift=TOLERATED
|disease=Defects in C7 are a cause of component C7 deficiency (C7D) (MIM:217070). Patients with C7D suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.
}}

{{PMID Auto
|PMID=19221116
|Title=Use of a genetic isolate to identify rare disease variants: C7 on 5p associated with MS.
|OA=1
}}

{{PMID Auto
|PMID=19344414
|Title=Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.
|OA=1
}}

{{GET Evidence
|gene=C7
|aa_change=Thr587Pro
|aa_change_short=T587P
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs13157656
|overall_frequency_n=1752
|overall_frequency_d=9638
|overall_frequency=0.18178
|n_genomes=21
|n_genomes_annotated=0
|n_haplomes=25
|n_articles=0
|n_articles_annotated=0
|nblosum100=4
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}