{{Rsnum
|rsid=1329428
|Gene=CFH
|Chromosome=1
|position=196733680
|Orientation=minus
|GMAF=0.4408
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CFH
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 17.9 | 49.1 | 33.0
| HCB | 15.8 | 44.4 | 39.8
| JPT | 25.2 | 44.1 | 30.6
| YRI | 30.5 | 51.8 | 17.7
| ASW | 14.0 | 57.9 | 28.1
| CHB | 15.8 | 44.4 | 39.8
| CHD | 24.3 | 39.3 | 36.4
| GIH | 34.3 | 42.4 | 23.2
| LWK | 16.8 | 42.1 | 41.1
| MEX | 12.5 | 55.4 | 32.1
| MKK | 11.7 | 39.0 | 49.4
| TSI | 24.5 | 43.1 | 32.4
| HapMapRevision=28
}}linked to blindness in [[age related macular degeneration]]

[[rs3753394]], [[rs800292]], [[rs1061147]], [[rs1061170]], [[rs380390]], and [[rs1329428]]

Significant associations were detected for [[AMD]] with 
[[rs3753394]]
[[rs800292]]
[[rs1329428]]

A haplotype of [[rs1061170]] [[rs3753394]] [[rs800292]] [[rs1329428]] (TGTC) was found to confer a significantly increased likelihood of exudative AMD

[[CFH]] variations appear to contribute to [[ARMD]] in Caucasians, but not in Japanese {{PMID|16710702}}

{{PMID Auto GWAS
|PMID=20861866
|Trait=None
|Title=Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration
|RiskAllele=
|Pval=3E-64
|OR=2.78
|ORtxt=[NR]
|OA=1
}}

{{PMID Auto
|PMID=15761122
|Title=Complement factor H polymorphism in age-related macular degeneration.
|OA=1
}}

{{PMID Auto
|PMID=16936733
|Title=CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration.
|OA=1
}}

{{PMID Auto
|PMID=17167412
|Title=Association of complement factor H polymorphisms with exudative age-related macular degeneration.
}}

{{PMID Auto
|PMID=18048322
|Title=A forest-based approach to identifying gene and gene gene interactions.
|OA=1
}}

{{PMID Auto
|PMID=18421087
|Title=Multiple gene polymorphisms in the complement factor h gene are associated with exudative age-related macular degeneration in chinese.
}}

{{PMID Auto
|PMID=19026761
|Title=Molecular pathology of age-related macular degeneration.
|OA=1
}}

{{PMID Auto
|PMID=19187823
|Title=Coding variant I62V in the complement factor H gene is strongly associated with polypoidal choroidal vasculopathy.
}}

{{PMID Auto
|PMID=19208169
|Title=A random forest approach to the detection of epistatic interactions in case-control studies.
|OA=1
}}

{{PMID Auto
|PMID=19412524
|Title=Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy.
|OA=1
}}

{{PMID Auto
|PMID=19958499
|Title=A particle swarm based hybrid system for imbalanced medical data sampling.
|OA=1
}}

{{PMID Auto
|PMID=20122224
|Title=A multi-filter enhanced genetic ensemble system for gene selection and sample classification of microarray data.
|OA=1
}}

{{PMID Auto
|PMID=20161815
|Title=SERPING1 polymorphisms in polypoidal choroidal vasculopathy.
|OA=1
}}

{{PMID Auto
|PMID=20181037
|Title=Incorporating prior knowledge to facilitate discoveries in a genome-wide association study on age-related macular degeneration.
|OA=1
}}

{{PMID Auto
|PMID=21111031
|Title=Correlation of complement factor H gene polymorphisms with exudative age-related macular degeneration in a Chinese cohort.
}}

{{PMID Auto
|PMID=21342556
|Title=The choice of null distributions for detecting gene-gene interactions in genome-wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=24365176
|Title=Common variants in the complement factor H gene confer genetic susceptibility to central serous chorioretinopathy
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}