{{Rsnum
|rsid=13321783
|Gene=GSK3B
|Chromosome=3
|position=119896528
|Orientation=plus
|GMAF=0.421
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=GSK3B
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 8.8 | 47.8 | 43.4
| HCB | 23.4 | 55.5 | 21.2
| JPT | 32.7 | 45.1 | 22.1
| YRI | 100.0 | 0.0 | 0.0
| ASW | 78.9 | 21.1 | 0.0
| CHB | 23.4 | 55.5 | 21.2
| CHD | 31.2 | 51.4 | 17.4
| GIH | 27.7 | 47.5 | 24.8
| LWK | 92.7 | 7.3 | 0.0
| MEX | 34.5 | 53.4 | 12.1
| MKK | 73.7 | 23.1 | 3.2
| TSI | 13.7 | 55.9 | 30.4
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs13321783
|Name_s=GSK3B: IVS7+11660 G>T
|Gene_s=GSK3B
|Feature=
|Evidence=PubMed ID:18195730
|Annotation=This variant is associated with antidepressant treatment response in Chinese major depressive disorder. In a four-locus haplotype analysis (rs334558; rs13321783; rs2319398; rs6808874), the GSK3B TAGT carriers showed a poorer response to antidepressants than carriers with other haplotype groups.
|Drugs=citalopram; fluoxetine
|Drug Classes=
|Diseases=Depression; Depressive Disorder, Major
|Curation Level=Curated
|PharmGKB Accession ID=PA162369929
}}

{{PMID|18195729}} Glycogen synthase kinase-3beta gene is associated with antidepressant treatment response in Chinese major depressive disorder.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs13321783
|overall_frequency_n=80
|overall_frequency_d=128
|overall_frequency=0.625
|n_genomes=45
|n_genomes_annotated=0
|n_haplomes=76
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}