{{Rsnum
|rsid=1335532
|Gene=CD58
|Chromosome=1
|position=116558335
|Orientation=minus
|GMAF=0.382
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CD58
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 2.7 | 22.1 | 75.2
| HCB | 32.8 | 46.0 | 21.2
| JPT | 47.8 | 35.4 | 16.8
| YRI | 32.9 | 47.9 | 19.2
| ASW | 24.6 | 49.1 | 26.3
| CHB | 32.8 | 46.0 | 21.2
| CHD | 31.2 | 49.5 | 19.3
| GIH | 11.9 | 39.6 | 48.5
| LWK | 46.4 | 40.9 | 12.7
| MEX | 10.3 | 36.2 | 53.4
| MKK | 45.5 | 37.0 | 17.5
| TSI | 1.0 | 26.5 | 72.5
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19525955
|Trait=Multiple sclerosis
|Title=Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
|RiskAllele=A
|Pval=1E-7
|OR=1.28
|ORtxt=[NR]
}}

{{PMID Auto
|PMID=20405052
|Title=The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1335532
|overall_frequency_n=48
|overall_frequency_d=128
|overall_frequency=0.375
|n_genomes=32
|n_genomes_annotated=0
|n_haplomes=42
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=21833088
  |Trait=Multiple sclerosis
  |Title=Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
  |RiskAllele=A
  |Pval=3E-16
  |OR=1.22
  |ORtxt=[1.19-1.24]
  |OA=1
}}

{{PMID Auto
|PMID=24655566
|Title=CD58 polymorphisms associated with the risk of neuromyelitis optica in a Korean population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}