{{Rsnum
|rsid=13376333
|Gene=KCNN3
|Chromosome=1
|position=154841877
|Orientation=plus
|GMAF=0.2199
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=KCNN3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 46.9 | 38.9 | 14.2
| HCB | 96.4 | 3.6 | 0.0
| JPT | 99.1 | 0.9 | 0.0
| YRI | 44.2 | 46.9 | 8.8
| ASW | 45.6 | 43.9 | 10.5
| CHB | 96.4 | 3.6 | 0.0
| CHD | 92.7 | 7.3 | 0.0
| GIH | 63.4 | 32.7 | 4.0
| LWK | 46.4 | 40.0 | 13.6
| MEX | 72.4 | 25.9 | 1.7
| MKK | 28.2 | 52.6 | 19.2
| TSI | 53.9 | 37.3 | 8.8
| HapMapRevision=28
}}
[http://www.theheart.org/article/1048707.do news] [[atrial fibrillation]] rs13376333 in [[KCNN3]], with an odds ratio (OR) of 1.5 per copy of [[rs13376333]](T); CI: 1.40–1.64, p = 1.83 × 10e-21.

[http://blog.23andme.com/2010/02/25/snpwatch-genetic-variant-associated-with-lone-atrial-fibrillation/ spitoon]

{{PMID Auto GWAS
|PMID=20173747
|Trait=Atrial fibrillation
|Title=Common variants in KCNN3 are associated with lone atrial fibrillation
|RiskAllele=T
|Pval=2E-21
|OR=1.52
|ORtxt=[1.40-1.64]
|OA=1
}}

{{PharmGKB
|RSID=rs13376333
|Name_s=
|Gene_s=KCNN3
|Feature=
|Evidence=PubMed ID:20173747
|Annotation=Risk or phenotype-associated allele: T . Phenotype: This variant is associated with lone atrial fibrillation. Study size: 1,335 cases; 12,844 referants. Study population/ethnicity: Cases-German AF Network, Heart and Vascular Health Study, the Cleveland Clinic and Massachusetts General Hospital. Significance metric(s): overall combined odds ratio = 1.52, 95% CI 1.40-1.64, P = 1.83 x 10(-21) . Type of association: CO;GN
|Drugs=
|Drug Classes=
|Diseases=Atrial Fibrillation
|Curation Level=Curated
|PharmGKB Accession ID=PA165291543
}}
{{PMID Auto
|PMID=21107608
|Title=Significant association of SNP rs2106261 in the ZFHX3 gene with atrial fibrillation in a Chinese Han GeneID population
}}

{{omim
|id=608583
|rsnum=13376333
}}

{{PMID Auto
|PMID=21760908
|Title=Association between variants on chromosome 4q25, 16q22 and 1q21 and atrial fibrillation in the Polish population
|OA=1
}}

{{PMID Auto
|PMID=22019810
|Title=Significant Association of rs13376333 in KCNN3 on Chromosome 1q21 With Atrial Fibrillation in a Taiwanese Population
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs13376333
|overall_frequency_n=24
|overall_frequency_d=128
|overall_frequency=0.1875
|n_genomes=18
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23428961
|Title=Common genetic polymorphism at 4q25 locus predicts atrial fibrillation recurrence after successful cardioversion.
|OA=1
}}

{{PMID Auto
|PMID=24978901
|Title=Association between SNP rs13376333 and rs1131820 in the KCNN3 gene and atrial fibrillation in the Chinese Han population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}