{{Rsnum
|rsid=136176
|Gene=APOL1
|Chromosome=22
|position=36265600
|Orientation=plus
|GMAF=0.1584
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=APOL1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 62.5 | 31.2 | 6.2
| HCB | 70.1 | 27.0 | 2.9
| JPT | 66.4 | 31.0 | 2.7
| YRI | 99.3 | 0.7 | 0.0
| ASW | 87.7 | 12.3 | 0.0
| CHB | 70.1 | 27.0 | 2.9
| CHD | 67.0 | 30.3 | 2.8
| GIH | 72.0 | 25.0 | 3.0
| LWK | 92.7 | 7.3 | 0.0
| MEX | 78.9 | 19.3 | 1.8
| MKK | 80.1 | 19.2 | 0.6
| TSI | 54.5 | 39.6 | 5.9
| HapMapRevision=28
}}Customers of 23andMe can use the presence of the A allele for coding SNP [[rs2239785]] (p.E150K) or the presence of the G allele for coding SNP [[rs136175]] (p.M228I) or coding SNP [[rs136176]] (p.R255K) to exclude the presence of alleles G1 and G2 of [[APOL1]], although absence of these alleles does not imply presence of either G1 or G2. Furthermore, presence of the T allele for SNP [[rs4419330]] excludes the presence of allele G2 and presence of the C allele for SNP rs4419330 excludes the presence of allele G1.

{{GET Evidence
|gene=APOL1
|aa_change=Arg271Lys
|aa_change_short=R271K
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs136176
|n_genomes=1
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|nblosum100=-3
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}