{{Rsnum
|rsid=137853964
|Gene=LDLR
|Chromosome=19
|position=11129602
|Orientation=plus
|GMAF=0.0004591
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LDLR
}}[[rs137853964]], also known as V827I, is a SNP in the low density lipoprotein receptor [[LDLR]] gene. 

This SNP is being studied in participants in the NIH ClinSeq program.{{PMID|19602640|OA=1
}}{{ClinVar
|rsid=137853964
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=11240278
|CHROM=19
|GMAF=0.0005
|dbSNPBuildID=133
|SSR=0
|SAO=1
|VP=0x050068000000040016100100
|GENEINFO=LDLR:3949
|GENE_NAME=LDLR
|GENE_ID=3949
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000019.9:g.11240278G>A
|CLNSRC=Correlagen
|CLNORIGIN=1
|CLNSIG=4
|CLNDBN=Familial hypercholesterolemia; not provided
|Disease=Familial hypercholesterolemia; not provided
|Tags=PM;PMC;VLD;KGPhase1;KGPROD;OTHERKG;LSD
|CAF=0.9995; 0.0004591
|CLNACC=RCV000030135.1; RCV000058923.1
|CLNDSDB=MedGen:OMIM:OMIM:SNOMED_CT:SNOMED_CT
|CLNDSDBID=C0020445:143890:144400:397915002:398036000
|COMMON=0
}}{{PMID|15823}} Beta-adrenergic stimulation of cyclic AMP content and parathyroid hormone release from isolated bovine parathyroid cells.

{{PMID|10735632}} Molecular genetic testing for familial hypercholesterolemia: spectrum of LDL receptor gene mutations in The Netherlands.

{{PMID|15701167|OA=1
}} Familial hypercholesterolemia in St-Petersburg: the known and novel mutations found in the low density lipoprotein receptor gene in Russia.

{{PMID|18400033}} Silent exonic mutations in the low-density lipoprotein receptor gene that cause familial hypercholesterolemia by affecting mRNA splicing.

{{PMID|19026292}} Longitudinal evaluation and assessment of cardiovascular disease in patients with homozygous familial hypercholesterolemia.

{{PMID|19118540}} Evaluation of high-resolution melting analysis for screening the LDL receptor gene.