{{Rsnum
|rsid=137853966
|geno1=(-;-)
|geno2=(-;G)
|geno3=(G;G)
|Chromosome=19
|Orientation=plus
|Gene=LDLR
|position=11105559
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=LDLR
}}The - (deletion) allele of this SNP in the low density lipoprotein receptor [[LDLR]] gene is a dominant mutation that causes [[familial hypercholesterolemia]]. {{PMID|7649546}}{{ClinVar
|rsid=137853966
|Reversed=0
|FwdREF=G
|FwdALT=
|REF=TG
|ALT=T
|RSPOS=11216233
|CHROM=19
|dbSNPBuildID=133
|SSR=0
|SAO=1
|VP=0x050268000000000002100200
|GENEINFO=LDLR:3949
|GENE_NAME=LDLR
|GENE_ID=3949
|WGT=0
|VC=DIV
|CLNALLE=1
|CLNHGVS=NC_000019.9:g.11216235delG
|CLNORIGIN=1
|CLNSIG=1
|Tags=PM;PMC;S3D;OTHERKG;LSD
|CLNACC=RCV000058918.1
|CLNDBN=not provided
|Disease=not provided
}}{{PMID Auto
|PMID=19602640
|Title=The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine.
|OA=1
}}