{{Rsnum
|rsid=1380866
|Gene=DSG3
|Chromosome=18
|position=31475994
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=G
|GMAF=0.001377
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=DSG3
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 0.9 | 99.1
| HCB | 0.0 | 0.7 | 99.3
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.7 | 99.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 1.7 | 98.3
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 3.9 | 96.1
| HapMapRevision=28
}}{{Venter SNP
|rsid=1380866
|allele=G
|frequency=1
|uid=1103645166872
|type=homozygous_SNP
|hugo=DSG3
|ensembl gene=ENSG00000134757
|ensembl transcript=ENST00000257189
|sift=TOLERATED
|disease=Pemphigus vulgaris (PV) is a potentially lethal skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion caused by the action of autoantibodies against desmoglein 3.
}}

{{GET Evidence
|gene=DSG3
|aa_change=Thr912Ala
|aa_change_short=T912A
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1380866
|overall_frequency_n=10739
|overall_frequency_d=10758
|overall_frequency=0.998234
|n_genomes=56
|n_genomes_annotated=0
|n_haplomes=111
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.001
|nblosum100=1
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}