{{Rsnum
|rsid=1386494
|Gene=TPH2
|Chromosome=12
|position=71958763
|Orientation=minus
|GMAF=0.1451
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=TPH2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 3.1 | 18.5 | 78.5
| HCB | 0.0 | 13.3 | 86.7
| JPT | 0.0 | 2.3 | 97.7
| YRI | 1.6 | 34.9 | 63.5
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 13.3 | 86.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}an association with [[rs1386494]] SNP was observed in the subgroup of female patients with pure PD phenotype, indicating a possible gender-specific effect of [[TPH2]] gene variants in [[panic disorder]].

{{PMID Auto
|PMID=19679166
|Title=TPH2 polymorphisms may modify clinical picture in treatment-resistant depression
}}
{{PMID Auto
|PMID=19590397
|Title=5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression
}}

{{PMID Auto
|PMID=21531467
|Title=Serotonin-related gene pathways associated with undifferentiated somatoform disorder
}}

{{PMID Auto
|PMID=17123728
|Title=Association study of tryptophan hydroxylase 2 gene polymorphisms in panic disorder.
}}

{{PMID Auto
|PMID=18832011
|Title=Association testing of panic disorder candidate genes using CCK-4 challenge in healthy volunteers.
}}

{{PMID Auto
|PMID=19184136
|Title=Examination of association of genes in the serotonin system to autism.
|OA=1
}}

{{PMID Auto
|PMID=19359258
|Title=Cohort profile: risk patterns and processes for psychopathology emerging during adolescence: the ROOTS project.
|OA=1
}}

{{PMID Auto
|PMID=19742166
|Title=Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features.
|OA=1
}}

{{PMID Auto
|PMID=21172166
|Title=Pharmacogenetics of antidepressant response.
|OA=1
}}

{{PMID Auto
|PMID=21621273
|Title=Association of polymorphisms in HTR2A, HTR1A and TPH2 genes with suicide attempts in alcohol dependence: a preliminary report.
|OA=1
}}

{{PMID Auto
|PMID=23063133
|Title=Genetics of emergent suicidality during antidepressive treatment--data from a naturalistic study on a large sample of inpatients with a major depressive episode.
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}