{{Rsnum
|rsid=1401296
|Chromosome=2
|position=127431732
|Orientation=plus
|GMAF=0.3255
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 18.5 | 40.0 | 41.5
| HCB | 17.8 | 57.8 | 24.4
| JPT | 9.1 | 56.8 | 34.1
| YRI | 4.8 | 31.7 | 63.5
| ASW | 0.0 | 0.0 | 0.0
| CHB | 17.8 | 57.8 | 24.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}[http://genetics.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pgen.0030120.eor linked] to Cardiovascular Events

Several CVD risk variants were identified: In women, the combination of F5 [[rs7542281]] Ã— THBD [[rs1042580]], together with three single F5 SNPs, was associated with CVD events. Among men, PROC [[rs1041296]], when combined with either ICAM1 [[rs5030341]] or F5 [[rs2269648]], was associated with total mortality. As a single variant, PROC [[rs1401296]], together with the F5 Leiden mutation, was associated with ischemic [[stroke]] events.{{PMID|17677000|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}