{{Rsnum
|rsid=1445898
|Gene=CAPSL
|Chromosome=5
|position=35910427
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.4844
|Gene_s=CAPSL
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|effect1=
|effect2=
|effect3=
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 19.5 | 36.3 | 44.2
| HCB | 60.0 | 36.3 | 3.7
| JPT | 68.1 | 28.3 | 3.5
| YRI | 4.8 | 23.3 | 71.9
| ASW | 3.5 | 49.1 | 47.4
| CHB | 60.0 | 36.3 | 3.7
| CHD | 59.8 | 33.6 | 6.5
| GIH | 48.5 | 31.7 | 19.8
| LWK | 13.0 | 40.7 | 46.3
| MEX | 42.1 | 40.4 | 17.5
| MKK | 14.2 | 45.8 | 40.0
| TSI | 22.8 | 46.5 | 30.7
| HapMapRevision=28
}}

[[rs1445898]] is associated with some protection from [[type-1 diabetes]] in several European populations.{{PMID|18563381}}

{{PMID Auto GWAS
|PMID=17554260
|Trait=Type 1 diabetes
|Title=Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
|RiskAllele=G
|Pval=0.0000079999999999999996
|OR=1.12
|ORtxt=[1.06-1.19]
|OA=1
}}

{{PMID Auto
|PMID=18556337
|Title=Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).
|OA=1
}}

{{PMID Auto
|PMID=18927125
|Title=IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.
|OA=1
}}

{{PMID Auto
|PMID=19956101
|Title=Overview of the Rapid Response data.
|OA=1
}}

{{PMID Auto
|PMID=19956106
|Title=Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
|OA=1
}}

{{PMID Auto
|PMID=19956109
|Title=The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.
|OA=1
}}

{{GET Evidence
|gene=CAPSL
|aa_change=Arg85Gln
|aa_change_short=R85Q
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1445898
|overall_frequency_n=4150
|overall_frequency_d=10756
|overall_frequency=0.385831
|n_genomes=32
|n_genomes_annotated=0
|n_haplomes=44
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|nblosum100=0
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}