{{Rsnum
|rsid=1455832
|Gene=ROBO1
|Chromosome=3
|position=79126966
|Orientation=minus
|GMAF=0.2287
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ROBO1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 6.2 | 53.8 | 40.0
| HCB | 4.4 | 35.6 | 60.0
| JPT | 2.3 | 38.6 | 59.1
| YRI | 4.8 | 23.8 | 71.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 4.4 | 35.6 | 60.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

[http://www.genengnews.com/news/bnitem.aspx?name=33143258 news] affects obesity strongest during childhood and diminishes after age 45.

{{omim
|desc=ROUNDABOUT, DROSOPHILA, HOMOLOG OF, 1; ROBO1
|id=602430
|rsnum=1455832
}}

{{PharmGKB
|RSID=rs1455832
|Name_s=
|Gene_s=ROBO1
|Feature=
|Evidence=PubMed ID:18387595
|Annotation=In a GWAS of the Framingham Heart Study cohort, this SNP showed significant association with BMI. In this study and in attempted replications, in five of eight additional cohorts examined, the CC genotype of this SNP was associated with increased BMI until age 45. After this age, the correlation decreased.
|Drugs=
|Drug Classes=
|Diseases=Obesity
|Curation Level=Curated
|PharmGKB Accession ID=PA162364074
}}

{{PMID Auto
|PMID=21412182
|Title=Association between the ROBO1 gene and body mass index in patients using antipsychotics
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1455832
|overall_frequency_n=100
|overall_frequency_d=128
|overall_frequency=0.78125
|n_genomes=54
|n_genomes_annotated=0
|n_haplomes=90
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}