{{Rsnum
|rsid=1456893
|Chromosome=7
|position=50230076
|Orientation=plus
|GMAF=0.3857
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 40.7 | 48.7 | 10.6
| HCB | 10.2 | 43.1 | 46.7
| JPT | 24.8 | 52.2 | 23.0
| YRI | 47.6 | 42.9 | 9.5
| ASW | 43.9 | 43.9 | 12.3
| CHB | 10.2 | 43.1 | 46.7
| CHD | 13.8 | 42.2 | 44.0
| GIH | 81.2 | 17.8 | 1.0
| LWK | 31.8 | 49.1 | 19.1
| MEX | 60.3 | 29.3 | 10.3
| MKK | 45.5 | 48.7 | 5.8
| TSI | 55.9 | 38.2 | 5.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18587394
|Trait=Crohn's disease
|Title=Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
|RiskAllele=A
|Pval=5.0000000000000001E-9
|OR=1.20
|ORtxt=[NR]
|OA=1
}}

DeCode reports that [[rs1456893]] is associated with susceptibility to [[Crohn's disease]]. {{PMID|18587394|OA=1
}}

{{PMID Auto
|PMID=19068216
|Title=Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
|OA=1
}}

{{PMID Auto
|PMID=21304977
|Title=An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
|OA=1
}}

{{PMID Auto
|PMID=21830272
|Title=Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1456893
|overall_frequency_n=92
|overall_frequency_d=128
|overall_frequency=0.71875
|n_genomes=54
|n_genomes_annotated=0
|n_haplomes=81
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}