{{Rsnum
|rsid=1457451
|Gene=LOC100131818
|Chromosome=2
|position=65635244
|Orientation=plus
|GMAF=0.1414
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 21.2 | 77.9
| HCB | 4.4 | 19.7 | 75.9
| JPT | 1.8 | 29.2 | 69.0
| YRI | 4.8 | 39.5 | 55.8
| ASW | 1.8 | 29.8 | 68.4
| CHB | 4.4 | 19.7 | 75.9
| CHD | 4.6 | 19.4 | 75.9
| GIH | 2.0 | 44.6 | 53.5
| LWK | 2.7 | 34.5 | 62.7
| MEX | 0.0 | 22.4 | 77.6
| MKK | 3.8 | 26.3 | 69.9
| TSI | 0.0 | 13.7 | 86.3
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19084217
|Trait=Serum markers of iron status
|Title=Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels
|RiskAllele=
|Pval=0.000003
|OR=NR
|ORtxt=NR
|OA=1
}}

{{PharmGKB
|RSID=rs1457451
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19084217; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (Initial Sample Size: 459 twin pairs; Replication Sample Size: NR); (Region: 2p14; Reported Gene(s): Q6ZNG6; Risk Allele: rs1457451-?); (p-value= 0.000003).This variant is associated with Serum markers of iron status.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740120
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1457451
|overall_frequency_n=23
|overall_frequency_d=128
|overall_frequency=0.179688
|n_genomes=19
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}