{{Rsnum
|rsid=1458175
|Gene=PDZRN4
|Chromosome=12
|position=41572059
|Orientation=minus
|GMAF=0.3228
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=PDZRN4
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 28.3 | 43.4 | 28.3
| HCB | 69.3 | 29.2 | 1.5
| JPT | 77.9 | 19.5 | 2.7
| YRI | 50.3 | 38.8 | 10.9
| ASW | 56.1 | 33.3 | 10.5
| CHB | 69.3 | 29.2 | 1.5
| CHD | 73.4 | 22.9 | 3.7
| GIH | 38.6 | 52.5 | 8.9
| LWK | 38.2 | 46.4 | 15.5
| MEX | 62.1 | 32.8 | 5.2
| MKK | 30.5 | 48.1 | 21.4
| TSI | 38.2 | 52.0 | 9.8
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19010793
|Trait=Multiple sclerosis
|Title=Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
|RiskAllele=
|Pval=0.000002
|OR=1.34
|ORtxt=[NR]
}}

{{PharmGKB
|RSID=rs1458175
|Name_s=
|Gene_s=PDZRN4
|Feature=
|Evidence=PubMed ID:19010793; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (Initial Sample Size: 978 cases, 883 controls; Replication Sample Size: NR); (Region: 12q12; Reported Gene(s): PDZRN4; Risk Allele: rs1458175-?); (p-value= 0.000002).This variant is associated with Multiple sclerosis.
|Drugs=
|Drug Classes=
|Diseases=Multiple Sclerosis
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740708
}}

{{PMID Auto
|PMID=20944657
|Title=Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1458175
|overall_frequency_n=88
|overall_frequency_d=128
|overall_frequency=0.6875
|n_genomes=50
|n_genomes_annotated=0
|n_haplomes=76
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}