{{Rsnum
|rsid=145999145
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Chromosome=19
|Orientation=plus
|Gene=PLD3
|position=40371688
|Gene_s=PLD3
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}[[rs145999145]], also known as Val232Met is a SNP in the phospholipase D family, member 3 [[PLD3]] gene on chromosome 19. The [[rs145999145]](G) allele encodes the Val; the (A) allele the Met. 

A relatively rare variant in this SNP has been linked to a doubling of risk for [[Alzheimer's disease]] based on seven independent case-control series with a total of more than 11,000 cases and controls of European descent. Other rare variants in the [[PLD3]] gene may also influence disease risk. {{PMID|24336208}}