{{Rsnum
|rsid=1478091
|Chromosome=4
|position=130869346
|Orientation=plus
|GMAF=0.1671
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.9 | 15.9 | 83.2
| HCB | 0.0 | 10.9 | 89.1
| JPT | 0.9 | 17.7 | 81.4
| YRI | 19.7 | 47.6 | 32.7
| ASW | 5.3 | 56.1 | 38.6
| CHB | 0.0 | 10.9 | 89.1
| CHD | 0.0 | 11.0 | 89.0
| GIH | 0.0 | 17.8 | 82.2
| LWK | 17.3 | 58.2 | 24.5
| MEX | 1.7 | 25.9 | 72.4
| MKK | 22.4 | 44.9 | 32.7
| TSI | 0.0 | 18.6 | 81.4
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19010793
|Trait=Multiple sclerosis (severity)
|Title=Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
|RiskAllele=
|Pval=0.000002
|OR=NR
|ORtxt=NR
}}

{{PharmGKB
|RSID=rs1478091
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19010793; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (Initial Sample Size: 794 cases, 883 controls; Replication Sample Size: NR); (Region: 4q28.3; Reported Gene(s): LOC132321; Risk Allele: rs1478091-?); (p-value= 0.000002).This variant is associated with Multiple sclerosis (severity).
|Drugs=
|Drug Classes=
|Diseases=Multiple Sclerosis
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740734
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1478091
|overall_frequency_n=97
|overall_frequency_d=128
|overall_frequency=0.757812
|n_genomes=51
|n_genomes_annotated=0
|n_haplomes=86
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}