{{Rsnum
|rsid=1487278
|Gene=TPH2
|Chromosome=12
|position=72007071
|Orientation=plus
|GMAF=0.2135
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TPH2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 4.6 | 35.4 | 60.0
| HCB | 4.4 | 46.7 | 48.9
| JPT | 9.1 | 52.3 | 38.6
| YRI | 0.0 | 20.6 | 79.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 4.4 | 46.7 | 48.9
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs1487278
|Name_s=
|Gene_s=TPH2
|Feature=
|Evidence=PubMed ID:18496129
|Annotation=This SNP was significantly associated with response to therapy in 182 patient who received treatment for major depression.
|Drugs=mirtazapine; venlafaxine
|Drug Classes=
|Diseases=Depression
|Curation Level=Curated
|PharmGKB Accession ID=PA162190497
}}

{{PMID Auto
|PMID=19184136
|Title=Examination of association of genes in the serotonin system to autism.
|OA=1
}}

{{PMID Auto
|PMID=21172166
|Title=Pharmacogenetics of antidepressant response.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1487278
|overall_frequency_n=12
|overall_frequency_d=128
|overall_frequency=0.09375
|n_genomes=11
|n_genomes_annotated=0
|n_haplomes=12
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}