{{Rsnum
|rsid=1495377
|Chromosome=12
|position=71183321
|Orientation=minus
|GMAF=0.3462
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 19.5 | 57.5 | 23.0
| HCB | 7.5 | 33.8 | 58.6
| JPT | 11.5 | 43.4 | 45.1
| YRI | 1.4 | 26.7 | 71.9
| ASW | 5.3 | 45.6 | 49.1
| CHB | 7.5 | 33.8 | 58.6
| CHD | 9.3 | 38.3 | 52.3
| GIH | 17.0 | 48.0 | 35.0
| LWK | 3.6 | 34.5 | 61.8
| MEX | 5.3 | 35.1 | 59.6
| MKK | 7.7 | 43.2 | 49.0
| TSI | 34.7 | 47.5 | 17.8
| HapMapRevision=28
}}
[[rs1495377]] has been reported in a large study to be associated with [[type-2 diabetes]].

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.28 (CI 1.11-1.49), and for homozygotes, 1.51 (CI 1.28-1.78). {{PMID|17554300|OA=1
}}

Note: orientation of this SNP is presumed correct but should be confirmed

{{GWAS Summary
|SNP=rs1495377
|PubMedID=17554300
|Condition=Type 2 diabetes
|Gene=NR
|Risk Allele=G
|pValue=7.00E-006
|OR=1.28
|95CI=1.11-1.49
|OA=1
}}

{{PharmGKB
|RSID=rs1495377
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,924 cases, 2,938 controls; Replication Sample Size: (see Zeggini 2007); Risk Allele: rs1495377-G). This variant is associated with type 2 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus; Diabetes Mellitus, Type 2
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356643
}}

{{PMID Auto GWAS
|PMID=22137330
|Trait=None
|Title=Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk.
|RiskAllele=
|Pval=0.000002
|OR=None
|ORtxt=None
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1495377
|overall_frequency_n=86
|overall_frequency_d=128
|overall_frequency=0.671875
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=78
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}