{{Rsnum
|rsid=1495965
|Gene=IL23R
|Chromosome=1
|position=67287825
|Orientation=minus
|GMAF=0.4522
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 36.0 | 45.9 | 18.0
| HCB | 21.6 | 55.2 | 23.1
| JPT | 31.5 | 49.5 | 18.9
| YRI | 28.3 | 53.1 | 18.6
| ASW | 28.1 | 50.9 | 21.1
| CHB | 21.6 | 55.2 | 23.1
| CHD | 24.1 | 50.0 | 25.9
| GIH | 21.8 | 48.5 | 29.7
| LWK | 37.3 | 43.6 | 19.1
| MEX | 51.7 | 41.4 | 6.9
| MKK | 29.0 | 50.3 | 20.6
| TSI | 28.0 | 51.0 | 21.0
| HapMapRevision=28
}}[[rs1495965]] is one of several SNPs in the [[IL23R]] gene that has been shown in a large (over 1,000 Caucasian patients) study to be associated with [[ankylosing spondylitis]]. The odds ratio is 1.2 (p=6.6x10e-6).[PMID 17952073, PMID 18037607]

23andMe reports that the CC genotype at [[rs1495965]] is associated with 1.56x higher odds of [[Behçet's disease]], and the TT genotype with 0.64x lower odds, than the CT genotype. {{PMID|20622879}}

{{PMID|18713787}} [[rs11209032]] and [[rs1495965]] no significant association with systemic sclerosis

{{PMID Auto
|PMID=19034457
|Title=Lack of association between interleukin 23 receptor gene polymorphisms and rheumatoid arthritis susceptibility
}}

{{PMID Auto
|PMID=19334001
|Title=Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans
}}

{{PMID Auto GWAS
|PMID=20622879
|Trait=Behcet's disease
|Title=Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci
|RiskAllele=G
|Pval=2E-11
|OR=1.35
|ORtxt=[1.24-1.47]
}}

{{PMID Auto
|PMID=22089529
|Title=Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis
}}

{{PMID|17068223}} A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

{{PMID|17678723}} Investigation of the IL23R gene in a Spanish rheumatoid arthritis cohort.

{{PMID|17786191|OA=1
}} rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

{{PMID|18200510}} CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population.

{{PMID|18470928|OA=1
}} IL23R haplotypes provide a large population attributable risk for Crohn's disease.

{{PMID|19175939|OA=1
}} IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease.

{{PMID|19306001}} No association between interleukin 23 receptor gene polymorphisms and systemic lupus erythematosus.

{{PMID|20454450|OA=1
}} Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.

{{PMID|21304977|OA=1
}} An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.

{{PMID|22378604}} Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behcet's disease.

{{PMID Auto
|PMID=24998354
|Title=Determination of IL-23 receptor gene polymorphism in Iranian patients with ankylosing spondylitis
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}