{{Rsnum
|rsid=1513670
|Chromosome=17
|position=43729963
|Orientation=minus
|GMAF=0.4082
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 14.2 | 49.6 | 36.3
| HCB | 38.0 | 48.2 | 13.9
| JPT | 21.2 | 56.6 | 22.1
| YRI | 22.4 | 43.5 | 34.0
| ASW | 8.8 | 54.4 | 36.8
| CHB | 38.0 | 48.2 | 13.9
| CHD | 41.3 | 45.9 | 12.8
| GIH | 8.9 | 32.7 | 58.4
| LWK | 18.3 | 34.9 | 46.8
| MEX | 17.2 | 48.3 | 34.5
| MKK | 16.0 | 46.8 | 37.2
| TSI | 9.8 | 52.9 | 37.3
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19079262
|Trait=Bone mineral density (hip)
|Title=New sequence variants associated with bone mineral density
|RiskAllele=A
|Pval=2E-8
|OR=0.08
|ORtxt=[0.05-0.10] SD decrease
}}

{{PharmGKB
|RSID=rs1513670
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19079262; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: New sequence variants associated with bone mineral density. (Initial Sample Size: 6,865 individuals; Replication Sample Size: 8,510 individuals); (Region: 17q21.31; Reported Gene(s): SOST; Risk Allele: rs1513670-A); (p-value= 0.00000002).This variant is associated with Bone mineral density (hip).
|Drugs=
|Drug Classes=
|Diseases=Bone Diseases; Bone Diseases, Metabolic
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740132
}}

{{PMID Auto
|PMID=20072603
|Title=Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
|OA=1
}}

{{PMID Auto
|PMID=20534768
|Title=OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.
|OA=1
}}

{{PMID Auto
|PMID=20554715
|Title=Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1513670
|overall_frequency_n=80
|overall_frequency_d=128
|overall_frequency=0.625
|n_genomes=48
|n_genomes_annotated=0
|n_haplomes=65
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}