{{Rsnum
|rsid=1532624
|Gene=CETP
|Chromosome=16
|position=56971567
|Orientation=minus
|GMAF=0.3062
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=CETP
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 29.2 | 49.6 | 21.2
| HCB | 46.0 | 46.7 | 7.3
| JPT | 52.2 | 36.3 | 11.5
| YRI | 85.0 | 14.3 | 0.7
| ASW | 71.9 | 24.6 | 3.5
| CHB | 46.0 | 46.7 | 7.3
| CHD | 49.5 | 42.2 | 8.3
| GIH | 21.8 | 48.5 | 29.7
| LWK | 85.5 | 14.5 | 0.0
| MEX | 43.1 | 41.4 | 15.5
| MKK | 56.4 | 35.3 | 8.3
| TSI | 36.6 | 43.6 | 19.8
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19060911
|Trait=HDL cholesterol
|Title=Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
|RiskAllele=C
|Pval=9E-94
|OR=0.21
|ORtxt=[NR] SD decrease
|OA=1
}}

{{PharmGKB
|RSID=rs1532624
|Name_s=rs1532624 (CETP) C>A
|Gene_s=CETP
|Feature=Intron
|Evidence=PubMed ID:20195290
|Annotation=Risk or phenotype-associated allele: A Phenotype: This SNP was associated with a greater reduction in total cholesterol after at least 1 week of statin use. This was replicated in a second cohort. Study size: 546 (original cohort); 100 (replication cohort). Study population/ethnicity: People taking statins; age 55 or older; Rotterdam Study; Netherlands. Significance metric(s): p = 0.04 (original); p = 0.011 (replication) Type of association: PD.
|Drugs=
|Drug Classes=HMG COA REDUCTASE INHIBITORS
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165291807
}}

{{PMID Auto GWAS
|PMID=20066028
|Trait=Cholesterol
|Title=Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels
|RiskAllele=
|Pval=3E-20
|OR=9.99
|ORtxt=[NR] mg/dl increase between hmz
|OA=1
}}

{{PharmGKB
|RSID=rs1532624
|Name_s=
|Gene_s=CETP
|Feature=Intron
|Evidence=PubMed ID:19060911; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (Initial Sample Size: 21,412 individuals; Replication Sample Size: NR); (Region: 16q13; Reported Gene(s): CETP; Risk Allele: rs1532624-C); (p-value= 9E-94).This variant is associated with HDL cholesterol.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740212
}}
{{PMID Auto
|PMID=21252145
|Title=Physical Activity Modifies the Effect of LPL, LIPC and CETP Polymorphisms on HDL-C Levels and the Risk of Myocardial Infarction in Caucasian Women
|OA=1
}}

{{omim
|id=118470
|rsnum=1532624
}}

{{PMID|16700901|OA=1
}} Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction.

{{PMID|18254975|OA=1
}} Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat.

{{PMID|19041386|OA=1
}} Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.

{{PMID|19682379|OA=1
}} TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population.

{{PMID|19951432|OA=1
}} Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

{{PMID|20031564|OA=1
}} Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.

{{PMID|20502693|OA=1
}} Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1532624
|overall_frequency_n=43
|overall_frequency_d=128
|overall_frequency=0.335938
|n_genomes=28
|n_genomes_annotated=0
|n_haplomes=36
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=23505323
  |Trait=HDL cholesterol
  |Title=Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
  |RiskAllele=A
  |Pval=1E-24
  |OR=.23
  |ORtxt=[0.19-0.27] unit increase
  |OA=1
}}

{{PMID Auto
|PMID=24160573
|Title=Cholesteryl Ester Transfer Protein rs1532624 Gene Polymorphism is Associated with Reduced Response to Statin Therapy
}}

{{PMID Auto
|PMID=24283500
|Title=CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}