{{Rsnum
|rsid=153734
|Gene=PRICKLE2-AS1
|Chromosome=3
|position=64092333
|Orientation=minus
|GMAF=0.3292
|Gene_s=PRICKLE2-AS1,PRICKLE2
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 56.6 | 32.7 | 10.6
| HCB | 35.8 | 49.6 | 14.6
| JPT | 36.3 | 52.2 | 11.5
| YRI | 31.3 | 53.1 | 15.6
| ASW | 35.1 | 47.4 | 17.5
| CHB | 35.8 | 49.6 | 14.6
| CHD | 39.6 | 49.1 | 11.3
| GIH | 65.3 | 26.7 | 7.9
| LWK | 16.4 | 48.2 | 35.5
| MEX | 73.7 | 22.8 | 3.5
| MKK | 18.2 | 45.5 | 36.4
| TSI | 71.3 | 27.7 | 1.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19303062
|Trait=Folate pathway vitamins
|Title=Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
|RiskAllele=T
|Pval=0.000007
|OR=0.29
|ORtxt=[0.13-0.45] ng/ml increase
|OA=1
}}

{{PharmGKB
|RSID=rs153734
|Name_s=
|Gene_s=PRICKLE2
|Feature=
|Evidence=PubMed ID:19303062; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations. (Initial Sample Size: 2,934 individuals; Replication Sample Size: 686 individuals); (Region: 3p14.1; Reported Gene(s): PRICKLE2; Risk Allele: rs153734-T); (p-value= 0.000007).This variant is associated with Folate pathway vitamins.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739922
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs153734
|overall_frequency_n=81
|overall_frequency_d=128
|overall_frequency=0.632812
|n_genomes=46
|n_genomes_annotated=0
|n_haplomes=69
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}