{{Rsnum
|rsid=1544791
|Gene=PDE4D
|Chromosome=5
|position=60143255
|Orientation=plus
|GMAF=0.4325
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PDE4D
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 10.6 | 50.4 | 38.9
| HCB | 51.1 | 45.9 | 3.0
| JPT | 59.5 | 35.1 | 5.4
| YRI | 12.2 | 45.6 | 42.2
| ASW | 17.5 | 49.1 | 33.3
| CHB | 51.1 | 45.9 | 3.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 11.9 | 36.6 | 51.5
| LWK | 19.4 | 44.4 | 36.1
| MEX | 5.2 | 36.2 | 58.6
| MKK | 7.1 | 37.7 | 55.2
| TSI | 3.9 | 39.2 | 56.9
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs1544791
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19426955
|Annotation=In a Genome Wide Association Study of White and Hispanic populations, the minor allele A of rs1544791 was significantly associated with protection from asthma. This association did not replicate in black populations studied; these populations have very different linkage disequilibrium patterns from the White and Hispanic populations, implying that this variant may be associated but not causal of the phenotype.
|Drugs=
|Drug Classes=
|Diseases=Asthma
|Curation Level=Curated
|PharmGKB Accession ID=PA164856894
}}

{{PMID|20698975|OA=1
}} Asthma-susceptibility variants identified using probands in case-control and family-based analyses.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1544791
|overall_frequency_n=72
|overall_frequency_d=128
|overall_frequency=0.5625
|n_genomes=44
|n_genomes_annotated=0
|n_haplomes=64
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23193110
|Title=RGS5 gene and therapeutic response to short acting bronchodilators in paediatric asthma patients
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}