{{Rsnum
|rsid=1545843
|Chromosome=12
|position=84170289
|Orientation=plus
|GMAF=0.4904
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 23.0 | 49.6 | 27.4
| HCB | 16.9 | 47.1 | 36.0
| JPT | 15.3 | 36.0 | 48.6
| YRI | 44.2 | 45.6 | 10.2
| ASW | 42.1 | 50.9 | 7.0
| CHB | 16.9 | 47.1 | 36.0
| CHD | 8.3 | 50.0 | 41.7
| GIH | 39.6 | 45.5 | 14.9
| LWK | 54.1 | 37.6 | 8.3
| MEX | 42.1 | 50.9 | 7.0
| MKK | 49.4 | 44.2 | 6.4
| TSI | 30.4 | 51.0 | 18.6
| HapMapRevision=28
}}[[rs1545843]] is one of two linked SNPs potentially associated (at a distance though) with the [[SLC6A15]] gene; the other is [[rs1031681]].

A GWAS study and meta-analysis ultimately including six independent samples, primarily Caucasion/European but also including an African-American sample, found that the [[rs1545843]](A) allele was associated with higher risk for major [[depression]], but only in individuals less than 55 years old and only when homozygous, with an odds ratio of 1.4 (p = 2 x 10e-8).{{PMID|21521612|OA=1
}}

{{PMID Auto
|PMID=22475622
|Title=A variant of the neuronal amino acid transporter SLC6A15 is associated with ACTH and cortisol responses and cognitive performance in unipolar depression
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}