{{Rsnum
|rsid=1558744
|Chromosome=12
|position=68110812
|Orientation=plus
|GMAF=0.3292
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 15.0 | 50.4 | 34.5
| HCB | 2.2 | 19.0 | 78.8
| JPT | 1.8 | 12.4 | 85.8
| YRI | 38.8 | 44.2 | 17.0
| ASW | 26.3 | 38.6 | 35.1
| CHB | 2.2 | 19.0 | 78.8
| CHD | 0.9 | 21.1 | 78.0
| GIH | 5.0 | 24.8 | 70.3
| LWK | 28.2 | 56.4 | 15.5
| MEX | 7.0 | 24.6 | 68.4
| MKK | 14.1 | 48.7 | 37.2
| TSI | 15.7 | 43.1 | 41.2
| HapMapRevision=28
}}A genome-wide association study using DNA samples from 1,052 individuals with [[ulcerative colitis]] and preexisting data from 2,571 controls, all of European ancestry, concluded that this SNP and several others were associated with altered risk for the disease.{{PMID|19122664|OA=1
}}

{{omim
|desc=INFLAMMATORY BOWEL DISEASE 26; IBD26
|id=612639
|rsnum=1558744
}}

{{PharmGKB
|RSID=rs1558744
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19122664; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. (Initial Sample Size: 1,022 cases, 2,503 controls; Replication Sample Size: 1,387 cases, 1,115 controls); (Region: 12q15; Reported Gene(s): IFNG, IL26, IL22; Risk Allele: rs1558744-A); (p-value= 0.000000000003).This variant is associated with Ulcerative colitis.
|Drugs=
|Drug Classes=
|Diseases=Colitis, Ulcerative
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740084
}}

{{PMID Auto GWAS
|PMID=20228799
|Trait=Ulcerative colitis
|Title=Genome-wide association identifies multiple ulcerative colitis susceptibility loci
|RiskAllele=A
|Pval=4E-12
|OR=1.16
|ORtxt=[NR]
|OA=1
}}

{{PMID Auto
|PMID=21304977
|Title=An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1558744
|overall_frequency_n=46
|overall_frequency_d=126
|overall_frequency=0.365079
|n_genomes=35
|n_genomes_annotated=0
|n_haplomes=46
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}