{{Rsnum
|rsid=1561570
|Gene=OPTN
|Chromosome=10
|position=13155726
|Orientation=plus
|GMAF=0.4518
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 20.4 | 52.2 | 27.4
| HCB | 28.5 | 49.6 | 21.9
| JPT | 22.1 | 46.9 | 31.0
| YRI | 3.4 | 38.8 | 57.8
| ASW | 17.9 | 39.3 | 42.9
| CHB | 28.5 | 49.6 | 21.9
| CHD | 30.3 | 55.0 | 14.7
| GIH | 22.8 | 53.5 | 23.8
| LWK | 5.5 | 39.1 | 55.5
| MEX | 19.0 | 50.0 | 31.0
| MKK | 11.5 | 43.6 | 44.9
| TSI | 21.6 | 47.1 | 31.4
| HapMapRevision=28
}}related to  [[Paget’s disease of bone]] [http://blog.23andme.com/2010/05/19/snpwatch-genetic-variants-associated-with-risk-of-pagets-disease-of-bone-identified/ 23andMe blog].

{{PMID Auto GWAS
|PMID=20436471
|Trait=Paget's disease
|Title=Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone
|RiskAllele=
|Pval=6E-13
|OR=1.54
|ORtxt=[1.37-1.72]
|OA=1
}}

{{omim
|id=602080
|rsnum=1561570
}}

{{PMID Auto GWAS
|PMID=21623375
|Trait=None
|Title=Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.
|RiskAllele=T
|Pval=4E-38
|OR=1.6700
|ORtxt=[1.54-1.80]
}}

{{PMID Auto
|PMID=22796589
|Title=Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}