{{Rsnum
|rsid=1569175
|Chromosome=2
|position=200157231
|Orientation=minus
|GMAF=0.1607
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 8.8 | 91.2
| HCB | 0.0 | 41.6 | 58.4
| JPT | 1.8 | 28.3 | 69.9
| YRI | 6.1 | 42.9 | 51.0
| ASW | 7.0 | 21.1 | 71.9
| CHB | 0.0 | 41.6 | 58.4
| CHD | 4.6 | 28.4 | 67.0
| GIH | 0.0 | 8.9 | 91.1
| LWK | 3.6 | 23.6 | 72.7
| MEX | 13.8 | 27.6 | 58.6
| MKK | 1.3 | 28.2 | 70.5
| TSI | 2.0 | 7.8 | 90.2
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19176441
|Trait=Treatment response for acute lymphoblastic leukemia
|Title=Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
|RiskAllele=T
|Pval=9E-7
|OR=2.73
|ORtxt=[1.52-4.93]
|OA=1
}}

{{PharmGKB
|RSID=rs1569175
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19176441; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. (Initial Sample Size: 487 children; Replication Sample Size: NR); (Region: 2q33.1; Reported Gene(s): C2orf47; Risk Allele: rs1569175-T); (p-value= 0.0000009).This variant is associated with Treatment response for acute lymphoblastic leukemia.
|Drugs=
|Drug Classes=
|Diseases=Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740036
}}

{{PharmGKB
|RSID=rs1569175
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19176441
|Annotation=This variant is associated with end-of-induction minimal risidual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) from 2 independent cohorts (GWAS result). Risk Allele: T, MAF= 0.11, combined P value= 9.43E-07.
|Drugs=
|Drug Classes=
|Diseases=Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA162470151
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1569175
|overall_frequency_n=95
|overall_frequency_d=128
|overall_frequency=0.742188
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=83
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}