{{Rsnum
|rsid=1570360
|Gene=VEGFA
|Chromosome=6
|position=43770093
|Orientation=plus
|GMAF=0.2241
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=VEGFA
}}This position is referred to as the -1154 position in many VEGF-associated publications. The normal (or wild type) form of this SNP is a (G). The (A) form reduces the activity of this gene, resulting in less [[VEGF]] protein.

Individuals with one or more [[rs1570360]](A) alleles are reported to be at about a 3 fold higher risk of developing [[Sudden Infant Death Syndrome]] {{PMID|16916659}}.

{{PMID Auto
|PMID=19429179
|Title=Association between promoter polymorphisms of vascular endothelial growth factor gene and sporadic Alzheimer's disease among Northern Chinese Han
}}
{{PMID Auto
|PMID=19308252
|Title=Genetic variation in VEGF does not contribute significantly to the risk of congenital cardiovascular malformation
|OA=1
}}
{{PMID Auto
|PMID=19594543
|Title=Effect of vascular endothelial growth factor polymorphisms on survival in advanced-stage non-small-cell lung cancer
}}

{{PMID Auto
|PMID=20082870
|Title=A Single Nucleotide Polymorphism in the Vascular Endothelial Growth Factor Gene Is Associated with Recurrence of Hepatocellular Carcinoma after Transplantation
}}

{{PMID Auto
|PMID=19233472
|Title=Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection
}}

{{PMID Auto
|PMID=20132989
|Title=Phenotype and Genotype Characteristics of Age-related Macular Degeneration in a Japanese Population
}}

{{PMID Auto
|PMID=20678803
|Title=Complement Factor H and High-Temperature Requirement A-1 Genotypes and Treatment Response of Age-related Macular Degeneration
}}
{{PMID Auto
|PMID=20950367
|Title=Association of Vascular Endothelial Growth Factor Gene Polymorphisms with Recurrent Spontaneous Abortion in Chinese Han Women
}}

{{omim
|id=192240
|rsnum=1570360
}}

{{PMID Auto
|PMID=22015057
|Title=Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study
}}

{{PMID Auto
|PMID=22167330
|Title=Polymorphism of vascular endothelial growth factor -1154G&gt;A (rs1570360) with cancer risk: a meta-analysis of 16 case-control studies
}}

{{PMID Auto
|PMID=22818823
|Title=Association of VEGF-A genetic polymorphisms with cancer risk and survival in advanced-stage oral squamous cell carcinoma patients
}}

{{PMID|16142870}} A functional variant of vascular endothelial growth factor is associated with severe ischemic complications in giant cell arteritis.

{{PMID|16216669}} Analysis of vascular endothelial growth factor (VEGF) functional variants in rheumatoid arthritis.

{{PMID|16395752}} Association between functional haplotypes of vascular endothelial growth factor and renal complications in Henoch-Schonlein purpura.

{{PMID|16613616|OA=1
}} Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort.

{{PMID|16685110}} Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.

{{PMID|16801663}} Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS.

{{PMID|17204151|OA=1
}} VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis.

{{PMID|17319747|OA=1
}} Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk.

{{PMID|17625508}} VEGF C-634G polymorphism is associated with protection from isolated ventricular septal defect: case-control and TDT studies.

{{PMID|18441306}} VEGF polymorphisms are associated with severity of diabetic retinopathy.

{{PMID|19551141|OA=1
}} Analysis of germline variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in familial and sporadic renal cell carcinoma.

{{PMID|19587357|OA=1
}} A systematic meta-analysis of genetic association studies for diabetic retinopathy.

{{PMID|19603096|OA=1
}} An analysis of growth, differentiation and apoptosis genes with risk of renal cancer.

{{PMID|19755511|OA=1
}} The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors.

{{PMID|19842071}} No association of VEGF polymorphims with Alzheimer's disease.

{{PMID|20140301}} VEGFA polymorphisms and cardiovascular anomalies in 22q11 microdeletion syndrome: a case-control and family-based study.

{{PMID|20389299|OA=1
}} Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.

{{PMID|20444917}} Association of vascular endothelial growth factor polymorphisms with nonproliferative and proliferative diabetic retinopathy.

{{PMID|20706635|OA=1
}} Human genetics of diabetic retinopathy: current perspectives.

{{PMID|21080079}} Gene polymorphism of vascular endothelial growth factor -1154 G>A is associated with hypertensive nephropathy in a Hispanic population.

{{PMID|21257617}} Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss.

{{PMID|21347390|OA=1
}} Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms.

{{PMID|21388351}} Vascular endothelial growth factor A and cardiovascular disease in rheumatoid arthritis patients.

{{PMID|21982816}} Contribution of VEGF polymorphisms to variation in VEGF serum levels in a healthy population.

{{PMID Auto
|PMID=23211130
|Title=Polymorphisms in the vascular endothelial growth factor gene associated with recurrent spontaneous miscarriage
}}

{{PMID Auto
|PMID=23404364
|Title=Polymorphisms in the VEGFA promoter are associated with susceptibility to hepatocellular carcinoma by altering promoter activity
}}

{{PMID Auto
|PMID=24177231
|Title=The RTK/ERK Pathway is associated with Prostate Cancer Risk on the SNP level: a pooled analysis of 41 sets of data from case-control studies
}}

{{PMID Auto
|PMID=24321896
|Title=Effect of Genetic Polymorphisms of Vascular Endothelial Growth Factor on Left Ventricular Hypertrophy in Patients With Systemic Hypertension
}}

{{PMID Auto
|PMID=22729570
|Title=AKT3, ANGPTL4, eNOS3, and VEGFA associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.
}}

{{PMID Auto
|PMID=22925497
|Title=The relation of vascular endothelial growth factor (VEGF) gene polymorphisms on VEGF levels and the risk of vasoocclusive crisis in sickle cell disease.
}}

{{PMID Auto
|PMID=23007311
|Title=VEGF genetic polymorphisms affect the responsiveness to sildenafil in clinical and postoperative erectile dysfunction.
}}

{{PMID Auto
|PMID=23545315
|Title=Further evidence for the contribution of the vascular endothelial growth factor gene in coronary artery disease susceptibility.
}}

{{PMID Auto
|PMID=23553563
|Title=VEGFA SNPs and transcriptional factor binding sites associated with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.
}}

{{PMID Auto
|PMID=24868559
|Title=The Associations between VEGF Gene Polymorphisms and Diabetic Retinopathy Susceptibility: A Meta-Analysis of 11 Case-Control Studies
}}

{{PMID Auto
|PMID=24935327
|Title=Haplotype Analysis on Chromosome 6p of Tumor Necrosis Factor Alpha, Vascular Endothelial Growth Factor A, and Interleukin-17F Alleles Associated With Corneal Transplant Rejection
}}

{{PMID Auto
|PMID=24940484
|Title=Association between vascular endothelial growth factor gene polymorphisms and bladder cancer risk
}}

{{PMID Auto
|PMID=25148899
|Title=Investigating the association of vascular endothelial growth factor polymorphisms with breast cancer: a Moroccan case-control study
}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}