{{Rsnum
|rsid=16853571
|Chromosome=4
|position=41751113
|Orientation=plus
|GMAF=0.06887
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 86.7 | 12.4 | 0.9
| HCB | 99.3 | 0.7 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 64.6 | 31.3 | 4.1
| ASW | 64.9 | 31.6 | 3.5
| CHB | 99.3 | 0.7 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 73.3 | 25.7 | 1.0
| LWK | 64.5 | 34.5 | 0.9
| MEX | 98.3 | 1.7 | 0.0
| MKK | 75.6 | 24.4 | 0.0
| TSI | 92.2 | 7.8 | 0.0
| HapMapRevision=28
}}

rs16853571 increases susceptibility to Crohn's disease 1.45 times for carriers of the A allele {{PMID|17435756|OA=1
}}

{{PMID Auto
|PMID=19262523
|Title=rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
}}

{{omim
|desc=INFLAMMATORY BOWEL DISEASE 1; IBD1
|id=266600
|rsnum=16853571
}}

{{PMID Auto
|PMID=21206965
|Title=IL23R, NOD2/CARD15, ATG16L1 and PHOX2B polymorphisms in a group of patients with Crohn's disease and correlation with sub-phenotypes
}}

{{PMID Auto
|PMID=17068223
|Title=A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
}}

{{PMID Auto
|PMID=18580884
|Title=Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}