{{Rsnum
|rsid=17236239
|Gene=CNTNAP2
|Chromosome=7
|position=147885213
|Orientation=plus
|GMAF=0.2388
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CNTNAP2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 39.8 | 49.6 | 10.6
| HCB | 64.2 | 29.9 | 5.8
| JPT | 60.7 | 33.9 | 5.4
| YRI | 89.8 | 9.5 | 0.7
| ASW | 84.2 | 15.8 | 0.0
| CHB | 64.2 | 29.9 | 5.8
| CHD | 59.6 | 36.7 | 3.7
| GIH | 50.5 | 42.6 | 6.9
| LWK | 91.7 | 8.3 | 0.0
| MEX | 56.1 | 33.3 | 10.5
| MKK | 67.1 | 27.1 | 5.8
| TSI | 41.6 | 44.6 | 13.9
| HapMapRevision=28
}}
{{PMID|18987363|OA=1
}} [[Speech]] development [[rs4431523]], [[rs17236239]] and significant associations (with P values from 0.01 to 5.0x10–5) between nonsense-word repetition and nine intronic SNPs ([[rs851715]], [[rs10246256]], [[rs2710102]], [[rs759178]], [[rs1922892]], [[rs2538991]], [[rs17236239]], [[rs2538976]], and [[rs2710117]])

[http://blog.23andme.com/2008/11/06/snpwatch-genetic-variant-linked-to-common-form-of-language-impairment/ 23andMe blog]

[http://genes2brains2mentalhealth.wordpress.com/2008/11/07/sintinap-is-a-nonword-that-makes-it-hard-to-read-nonwords/ g2b2mh] discusses this snp

[http://content.nejm.org/cgi/content/short/359/22/2337 nejm]

{{omim
|desc=SPECIFIC LANGUAGE IMPAIRMENT 4; SLI4
|id=612514
|rsnum=17236239
}}

{{PharmGKB
|RSID=rs17236239
|Name_s=
|Gene_s=CNTNAP2
|Feature=
|Evidence=PubMed ID:18987363
|Annotation=This SNP in the CNTNAP2 gene was significantly associated with nonsense-word repetition in children with typical specific language impairment.
|Drugs=
|Drug Classes=
|Diseases=Language Disorders
|Curation Level=Curated
|PharmGKB Accession ID=PA162360048
}}

{{PMID|21310003|OA=1
}} CNTNAP2 variants affect early language development in the general population.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs17236239
|overall_frequency_n=28
|overall_frequency_d=128
|overall_frequency=0.21875
|n_genomes=21
|n_genomes_annotated=0
|n_haplomes=24
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23123147
|Title=CNTNAP2 is significantly associated with schizophrenia and major depression in the Han Chinese population.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}