{{Rsnum
|rsid=17266594
|Gene=BANK1
|Chromosome=4
|position=101829765
|Orientation=plus
|GMAF=0.225
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=BANK1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 7.1 | 38.1 | 54.9
| HCB | 1.5 | 29.9 | 68.6
| JPT | 0.9 | 20.4 | 78.8
| YRI | 4.8 | 40.1 | 55.1
| ASW | 1.8 | 29.8 | 68.4
| CHB | 1.5 | 29.9 | 68.6
| CHD | 0.0 | 23.9 | 76.1
| GIH | 7.9 | 30.7 | 61.4
| LWK | 2.7 | 38.2 | 59.1
| MEX | 0.0 | 22.4 | 77.6
| MKK | 10.3 | 48.7 | 41.0
| TSI | 7.8 | 42.2 | 50.0
| HapMapRevision=28
}}[[rs17266594]] [[rs10516487]] [[rs3733197]] gene associated with systemic [[lupus]] erythematosus.{{PMID|18204447}}

The association between [[rs17266594]] and [[lupus]] was replicated in a study of 1892 European-derived SLE patients and 2652 European-derived controls; the odds ratio observed was 1.22 (CI: 1.12-1.34, corrected p-value=1.97 x 10e-5).{{PMID|19339986|OA=1
}}

{{ neighbor
| rsid = 10516487
| distance = 154
}}

{{PMID Auto
|PMID=19357697
|Title=Association of BANK1 and TNFSF4 with systemic lupus erythematosus in Hong Kong Chinese.
|OA=1
}}

{{omim
|desc=B-CELL SCAFFOLD PROTEIN WITH ANKYRIN REPEATS 1; BANK1
|id=610292
|rsnum=17266594
}}
{{PMID Auto
|PMID=19714582
|Title=Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors
}}
{{PMID Auto
|PMID=19815934
|Title=BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians
|OA=1
}}

{{PharmGKB
|RSID=rs17266594
|Name_s=
|Gene_s=BANK1
|Feature=
|Evidence=PubMed ID:18204447
|Annotation=This variant is in strong linkage disequilibrium with rs10516487, associated with systemic lupus erythematosus. The study showed that the BANK1 gene can be expressed in two isoforms, one full-length and the other alternatively spliced and lacking exon 2. The transcripts were differentially expressed depending on this SNP.
|Drugs=
|Drug Classes=
|Diseases=Lupus Erythematosus, Systemic
|Curation Level=Curated
|PharmGKB Accession ID=PA161925606
}}

{{PMID Auto
|PMID=21208380
|Title=The association between BANK1 and TNFAIP3 gene polymorphisms and systemic lupus erythematosus: a meta-analysis
}}

{{PMID Auto
|PMID=21900951
|Title=The dual effect of the lupus-associated polymorphism rs10516487 on BANK1 gene expression and protein localization
|OA=1
}}

{{PMID Auto
|PMID=21989138
|Title=Association analysis of BANK1 gene with psoriasis in Southern Han Chinese
}}

{{PMID|19180476}} Study of functional variants of the BANK1 gene in rheumatoid arthritis.

{{PMID|19442287|OA=1
}} Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study.

{{PMID|20472928}} Role of BANK1 gene polymorphisms in biopsy-proven giant cell arteritis.

{{PMID|21078628}} Identification of BANK1 polymorphisms by unlabelled probe high resolution melting: association with systemic lupus erythematosus susceptibility and autoantibody production in Han Chinese.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs17266594
|overall_frequency_n=2528
|overall_frequency_d=9738
|overall_frequency=0.259602
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=22
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23406209
|Title=Association of ZAP70 and PTPN6, but Not BANK1 or CLEC2D, with inflammatory bowel disease in the Tunisian population.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}