{{Rsnum
|rsid=17373080
|Gene=NR1H2
|Chromosome=19
|position=50376267
|Orientation=plus
|GMAF=0.2713
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=NR1H2
}}[http://7thspace.com/headlines/305475/functional_and_genetic_analysis_in_type_2_diabetes_of_liver_x_receptor_alleles___a_cohort_study.html news] [[rs35463555]] and [[rs17373080]], associated nominally with [[type-2 diabetes]].

The [[rs17373080]] C allele displayed higher basal transcription activity (P value <0.05). The DNA-mobility shift assay indicated that oligonucleotides corresponding to either rs17373080 allele bound NF1 transcription factors in whole cell extracts to the same extent.
{{PMID Auto
|PMID=19292929
|Title=Functional and genetic analysis in type 2 diabetes of Liver X receptor alleles - a cohort study.
|OA=1
}}
{{PMID Auto
|PMID=20939869
|Title=Suggestive evidence of associations between liver X receptor beta polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT 2 (Norway), MONICA (France) and HELENA (Europe)
|OA=1
}}

{{PMID Auto
|PMID=24100084
|Title=Lack of association between LXRα and LXRβ gene polymorphisms and prevalence of metabolic syndrome: a case-control study of an Iranian population
}}

{{PMID Auto
|PMID=24788534
|Title=Liver X Receptor Gene Polymorphisms in Tuberculosis: Effect on Susceptibility
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}