{{Rsnum
|rsid=174575
|Gene=FADS2
|Chromosome=11
|position=61834531
|Orientation=plus
|GMAF=0.2328
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=FADS2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 50.8 | 44.6 | 4.6
| HCB | 80.0 | 17.8 | 2.2
| JPT | 81.8 | 15.9 | 2.3
| YRI | 54.0 | 36.5 | 9.5
| ASW | 0.0 | 0.0 | 0.0
| CHB | 80.0 | 17.8 | 2.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

[[rs174575]], has been investigated with respect to increased intelligence in breastfed children but not yielded any clear result. 
*Although there was no difference in IQ linked to the SNP alone, breastfed children carrying one or two copies of [[rs174575(C)]] had a significant (6 point) increase in IQ compared to carriers of the same allele who were not breastfed. For children who were homozygous non-carriers, i.e. [[rs174575(G;G)]] individuals, there was no effect of breastfeeding on IQ. {{PMID|17984066|OA=1
}}
*did not replicate those findings. In contrast to their study, (G;G) children exhibited the greatest difference between feeding methods such that breastfed children performed similarly irrespective of child genotype whereas formula fed (G;G) children performed worse than other children on formula milk {{PMID|20644632|OA=1
}}  

{{PMID Auto
|PMID=20335541
|Title=FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk
}}

{{PMID Auto
|PMID=20395685
|Title=Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study
}}

{{PMID Auto
|PMID=18936223
|Title=Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation.
}}

{{PMID Auto
|PMID=20565855
|Title=Genetic variation in lipid desaturases and its impact on the development of human disease.
|OA=1
}}

{{PMID Auto
|PMID=21040914
|Title=FADS gene polymorphisms in Koreans: association with omega6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease.
}}

{{PMID Auto
|PMID=21156270
|Title=Cognitive function in adolescence: testing for interactions between breast-feeding and FADS2 polymorphisms.
}}

{{PMID Auto
|PMID=21793953
|Title=FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children.
}}

{{PMID Auto
|PMID=22194195
|Title=Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphisms.
|OA=1
}}

[[Breastfeeding and IQ]]

{{PMID Auto
|PMID=23636240
|Title=FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants.
}}

{{PMID Auto
|PMID=23737301
|Title=A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems.
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}