{{Rsnum
|rsid=1748195
|Gene=DOCK7
|Chromosome=1
|position=62583922
|Orientation=plus
|GMAF=0.3792
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=DOCK7
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 42.5 | 46.9 | 10.6
| HCB | 57.7 | 36.5 | 5.8
| JPT | 71.7 | 25.7 | 2.7
| YRI | 6.2 | 38.6 | 55.2
| ASW | 15.8 | 45.6 | 38.6
| CHB | 57.7 | 36.5 | 5.8
| CHD | 55.0 | 40.4 | 4.6
| GIH | 32.0 | 45.0 | 23.0
| LWK | 7.3 | 40.0 | 52.7
| MEX | 49.1 | 31.6 | 19.3
| MKK | 20.6 | 45.8 | 33.5
| TSI | 46.1 | 42.2 | 11.8
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs1748195
|PubMedID=18193043
|Condition=Triglycerides
|Gene=ANGPTL3
|Risk Allele=C
|pValue=2.00E-010
|OR=7.12
|95CI=NR) mg/dl highe
}}

{{PharmGKB
|RSID=rs1748195
|Name_s=
|Gene_s=DOCK7
|Feature=
|Evidence=PubMed ID:18193043; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Newly identified loci that influence lipid concentrations and risk of coronary artery disease (Initial Sample Size: 8,684 individuals; Replication Sample Size: 5,312-9,707 individuals; Risk Allele: rs1748195-C). This variant is associated with triglyceride levels.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases; Coronary Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356709
}}

{{PMID Auto
|PMID=18852197
|Title=Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
|OA=1
}}

{{PMID Auto
|PMID=19060910
|Title=Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|OA=1
}}

{{PMID Auto
|PMID=19185284
|Title=Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
|OA=1
}}

{{PMID Auto
|PMID=19299407
|Title=Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.
|OA=1
}}

{{PMID Auto
|PMID=19435741
|Title=Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.
|OA=1
}}

{{PMID Auto
|PMID=19656773
|Title=A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.
|OA=1
}}

{{PMID Auto
|PMID=20369022
|Title=Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1748195
|overall_frequency_n=54
|overall_frequency_d=116
|overall_frequency=0.465517
|n_genomes=33
|n_genomes_annotated=0
|n_haplomes=46
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23832694
|Title=Common genetic variants associated with lipid profiles in a Chinese pediatric population.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}