{{Rsnum
|rsid=1751034
|Gene=ABCC4
|Chromosome=13
|position=95062722
|Orientation=plus
|GMAF=0.2245
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ABCC4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.9 | 26.5 | 72.6
| HCB | 5.1 | 34.6 | 60.3
| JPT | 8.8 | 47.8 | 43.4
| YRI | 7.5 | 40.1 | 52.4
| ASW | 3.5 | 36.8 | 59.6
| CHB | 5.1 | 34.6 | 60.3
| CHD | 7.3 | 30.3 | 62.4
| GIH | 2.0 | 23.2 | 74.7
| LWK | 10.9 | 45.5 | 43.6
| MEX | 3.5 | 52.6 | 43.9
| MKK | 19.2 | 41.1 | 39.7
| TSI | 6.9 | 32.4 | 60.8
| HapMapRevision=28
}}

{{PharmGKB
|RSID=rs1751034
|Name_s=ABCC4: 3463 A>G
|Gene_s=ABCC4
|Feature=Exon/Syn
|Evidence=PubMed ID:17597712; PubMed ID:18398970
|Annotation=This variant may influence tenofovir pharmacokenetics. It is associated with 35% increase in intracellular tenofovir diphosphate concentrations. Carriers of this variant had 15% lower than wild type renal clearance, and 35% higher than wild type AUC.
|Drugs=tenofovir
|Drug Classes=
|Diseases=HIV; HIV Infections
|Curation Level=Curated
|PharmGKB Accession ID=PA162359982
}}

{{PMID Auto
|PMID=18364470
|Title=The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1751034
|overall_frequency_n=8581
|overall_frequency_d=10758
|overall_frequency=0.797639
|n_genomes=52
|n_genomes_annotated=0
|n_haplomes=84
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | Affy GenomeWide 6}}