{{Rsnum
|rsid=17608
|Gene=CLC
|Chromosome=19
|position=39735006
|Orientation=minus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.4063
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CLC
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 9.7 | 41.6 | 48.7
| HCB | 39.4 | 48.9 | 11.7
| JPT | 38.9 | 50.4 | 10.6
| YRI | 4.1 | 35.6 | 60.3
| ASW | 1.8 | 42.1 | 56.1
| CHB | 39.4 | 48.9 | 11.7
| CHD | 43.1 | 47.7 | 9.2
| GIH | 8.9 | 45.5 | 45.5
| LWK | 2.8 | 32.1 | 65.1
| MEX | 25.9 | 53.4 | 20.7
| MKK | 5.1 | 37.2 | 57.7
| TSI | 8.9 | 37.6 | 53.5
| HapMapRevision=28
}}

{{Venter SNP
|rsid=17608
|allele=A
|frequency=0.292
|uid=1103691144485
|type=heterozygous_SNP
|hugo=CLC
|ensembl gene=ENSG00000105205
|ensembl transcript=ENST00000221804
|sift=TOLERATED
|disease=Forms hexagonal bipyramidal crystals, known as Charcot- Leyden crystals, in tissues and secretions from sites of eosinophil-associated inflammation and some myeloid leukemias.
}}

{{PMID Auto
|PMID=16015083
|Title=Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patients.
}}

{{GET Evidence
|gene=CLC
|aa_change=Ala28Val
|aa_change_short=A28V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs17608
|overall_frequency_n=7530
|overall_frequency_d=10758
|overall_frequency=0.699944
|n_genomes=47
|n_genomes_annotated=0
|n_haplomes=65
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|nblosum100=2
|autoscore=1
|n_web_uneval=7
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}