{{Rsnum
|rsid=17632542
|Gene=KLK3
|Chromosome=19
|position=50858501
|Orientation=plus
|GMAF=0.03168
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=KLK3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 16.8 | 83.2
| HCB | 0.0 | 0.7 | 99.3
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 1.8 | 98.2
| CHB | 0.0 | 0.7 | 99.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 9.9 | 90.1
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 5.2 | 94.8
| MKK | 0.0 | 0.0 | 0.0
| TSI | 2.0 | 9.8 | 88.2
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=21160077
|Trait=None
|Title=Genetic Correction of PSA Values Using Sequence Variants Associated with PSA Levels
|RiskAllele=T
|Pval=3E-46
|OR=39.1000
|ORtxt=[NR] % increase
|OA=1
}}

{{PMID Auto
|PMID=21465221
|Title=Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript
|OA=1
}}

{{PMID|21318478|OA=1
}} Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels.

{{GET Evidence
|gene=KLK3
|aa_change=Ile179Thr
|aa_change_short=I179T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs17632542
|overall_frequency_n=5
|overall_frequency_d=128
|overall_frequency=0.0390625
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23359319
|Title=Genome-wide Association Study Identifies Loci at ATF7IP and KLK2 Associated with Percentage of Circulating Free PSA
|OA=1
}}

{{PMID Auto
|PMID=23937305
|Title=Validation of association of genetic variants at 10q with prostate-specific antigen (PSA) levels in men at high risk for prostate cancer
}}

{{PMID Auto
|PMID=24345439
|Title=Prostate cancer risk alleles are associated with prostate cancer tumor volume and prostate size
}}

{{PMID Auto
|PMID=23246478
|Title=Personalized prostate specific antigen testing using genetic variants may reduce unnecessary prostate biopsies.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}