{{Rsnum
|rsid=17672135
|Gene=FMN2
|Chromosome=1
|position=240282296
|Orientation=plus
|GMAF=0.1084
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=FMN2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 2.7 | 22.3 | 75.0
| HCB | 2.2 | 16.8 | 81.0
| JPT | 2.7 | 25.7 | 71.7
| YRI | 0.0 | 15.0 | 85.0
| ASW | 0.0 | 19.3 | 80.7
| CHB | 2.2 | 16.8 | 81.0
| CHD | 0.0 | 16.5 | 83.5
| GIH | 2.0 | 28.7 | 69.3
| LWK | 3.6 | 14.5 | 81.8
| MEX | 0.0 | 12.3 | 87.7
| MKK | 0.0 | 11.5 | 88.5
| TSI | 2.0 | 13.7 | 84.3
| HapMapRevision=28
}}
[[rs17672135]] has been reported in a large study to be associated with [[heart disease]], in particular, [[coronary artery disease]].

The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 0.70 (CI 0.61-0.81), and for homozygotes, 1.32 (CI 0.79-2.22). {{PMID|17554300|OA=1
}}

{{GWAS Summary
|SNP=rs17672135
|PubMedID=17554300
|Condition=Coronary disease
|Gene=NR
|Risk Allele=C
|pValue=2.00E-006
|OR=1.43
|95CI=1.23-1.64
|OA=1
}}

{{PharmGKB
|RSID=rs17672135
|Name_s=
|Gene_s=FMN2
|Feature=
|Evidence=PubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,926 cases, 2,938 controls; Replication Sample Size: (see Samani 2007); Risk Allele: rs17672135-C). This variant is associated with coronary disease.
|Drugs=
|Drug Classes=
|Diseases=Coronary Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356645
}}

{{PMID Auto
|PMID=19956433
|Title=Genetics of coronary artery disease: focus on genome-wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=20017983
|Title=Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs17672135
|overall_frequency_n=14
|overall_frequency_d=128
|overall_frequency=0.109375
|n_genomes=11
|n_genomes_annotated=0
|n_haplomes=11
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}