{{Rsnum
|rsid=1769259
|Gene=FBP1
|Chromosome=9
|position=94606867
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.0225
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=FBP1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 91.2 | 8.8 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 97.3 | 2.7 | 0.0
| ASW | 96.5 | 3.5 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 99.1 | 0.9 | 0.0
| GIH | 86.1 | 13.9 | 0.0
| LWK | 99.1 | 0.9 | 0.0
| MEX | 94.8 | 5.2 | 0.0
| MKK | 99.4 | 0.6 | 0.0
| TSI | 91.2 | 8.8 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=1769259
|allele=T
|frequency=0.95
|uid=1103652132489
|type=homozygous_SNP
|hugo=FBP1
|ensembl gene=ENSG00000165140
|ensembl transcript=ENST00000375326
|sift=TOLERATED
|disease=Defects in FBP1 are the cause of fructose-1,6- bisphosphatase deficiency (FBPD) (MIM:229700). FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.
}}

{{GET Evidence
|gene=FBP1
|aa_change=Arg218Lys
|aa_change_short=R218K
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1769259
|overall_frequency_n=10265
|overall_frequency_d=10758
|overall_frequency=0.954174
|n_genomes=37
|n_genomes_annotated=0
|n_haplomes=63
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=-3
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}