{{Rsnum
|rsid=17708472
|Gene=VKORC1
|Chromosome=16
|position=31094032
|Orientation=plus
|GMAF=0.118
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=VKORC1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 4.4 | 38.1 | 57.5
| HCB | 0.0 | 0.0 | 0.0
| JPT | 0.0 | 0.0 | 0.0
| YRI | 0.0 | 4.1 | 95.9
| ASW | 0.0 | 10.5 | 89.5
| CHB | 0.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 1.0 | 28.7 | 70.3
| LWK | 0.0 | 10.9 | 89.1
| MEX | 1.7 | 32.8 | 65.5
| MKK | 0.0 | 15.4 | 84.6
| TSI | 2.0 | 26.5 | 71.6
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs17708472
|Name_s=VKORC1: 6009C>T; 698C>T
|Gene_s=VKORC1
|Feature=
|Evidence=PubMed ID:16270629
|Annotation=This SNP is the tagging SNP for VKORC1*4.
|Drugs=warfarin
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA162356241
}}

{{PMID Auto
|PMID=21127708
|Title=Genetic Variation of VKORC1 and CYP4F2 Genes Related to Warfarin Maintenance Dose in Patients with Myocardial Infarction
|OA=1
}}

{{PMID Auto
|PMID=22118051
|Title=Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversity
}}

{{PMID Auto
|PMID=18252229
|Title=Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.
|OA=1
}}

{{PMID Auto
|PMID=18855533
|Title=VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.
|OA=1
}}

{{PMID Auto
|PMID=19436136
|Title=Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs17708472
|overall_frequency_n=20
|overall_frequency_d=128
|overall_frequency=0.15625
|n_genomes=13
|n_genomes_annotated=0
|n_haplomes=16
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=10
}}

{{PMID Auto
|PMID=23662025
|Title=Genetic variation and haplotype structure of the gene Vitamin K epoxide reductase complex, subunit 1 in the Tamilian population
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}